The Amy K Walker Lab:
Department of Molecular Medicine
UMASS Medical School
We study how metabolites act as signals to control gene expression and lipid accumulation
The Walker lab uses worms, cells and mice to study how metabolites like the methyl-donor SAM or the methylated phospholipid PC regulate gene expression, the activity of the lipogenic transcription factor SREBP-1 and how bacterial metabolites can affect lipid accumulation in multicellular animals.